PD Dr. Johanna M. Brandner
Department
of Dermatology and Venerology
University Hospital Hamburg-Eppendorf
Campus Forschung - Dermatologie
Labor für Zell- und Molekularbiologie
N 27
Martinistraße 52
20246 Hamburg
Germany
brandner@uke.de
Research
focus
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Involvement of Tight Junctions in barrier function of epidermis and hair follicles
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Extrinsic and intrinsic influences on (epidermal) wound healing
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Establishment of ex vivo and in vitro skin models for wound healing, infection, barrier research and drug testing
Important publications
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Ohnemus U, Kohrmeyer K, Houdek P, Rohde H, Wladykwoski E, Vidal S, Horstkotte MA, Aepfelbacher M, Kirschner N, Behne MJ, Moll I, Brandner JM. Regulation of epidermal Tight Junctions (TJ) during infection with exfoliative toxin-negative Staphylococcus strains. J Invest Dermatol, 2007 Oct 4; [Epub ahead of print]
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Brandner JM, Zacheja, S, Houdek P, Moll I, Lobmann R. Expression of matrix metalloproteinases, cytokines and connexins in diabetic and non-diabetic human keratinocytes before and after transplantation into an ex-vivo wound healing model. Diabetes Care, 2007 Sep 26; [Epub ahead of print].
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Neub A, Houdek P, Ohnemus U, Moll I, Brandner JM. Biphasic regulation of AP-1 subunits during human epidermal wound healing. J Invest Dermatol 127:2453-2462, 2007
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Brandner JM, Kief S, Wladykowski E, Houdek P, Moll I. Tight junction proteins in the skin. Skin Pharmacol Physiol 19:71-77, 2006
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Haass NK, Wladykowski E, Kief S, Moll I and Brandner JM. Differential induction of connexins 26 and 30 in skin tumors and their adjacent epidermis. J Histochem Cytochem 54:171-182, 2006
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Brandner JM, Houdek P, Hüsing B, Kaiser C and Moll I. Connexins 26, 30 and 43: Differences between spontaneous, chronic and accelerated human wound healing. J. Invest. Dermatol. 122:1310-1320, 2004
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Meyer CG, Amedofu GK, Brandner JM, Pohland D, Timmann C and Horstmann RD. Selection for deafness? Nat. med. 8:1332-1333, 2002