Dr. Peter Caspers
Center
for Optical Diagnostics and Therapy
Department of General Surgery
Erasmus MC, Dr Molewaterplein 50, room wk331
3015 GE Rotterdam
The Netherlands
p.caspers@erasmusmc.nl
River Diagnostics BV
P.O. Box 25229
3001 HE Rotterdam
www.RiverD.com
Research
focus
-
In vivo confocal Raman microspectroscopy of the skin
-
Molecular epidermal gradients: water, free amino acids, lipids, topically applied products etc
-
Molecular characterization of healthy and diseased skin
Important publications
-
Pudney P.D.A, Mélot M, Caspers PJ, Pol A. van der, Puppels GJ. An in vivo Confocal Raman study of the delivery of trans-retinol to the skin. Appl Spectr 61(8), 2007
-
Wascotte V, Caspers PJ, Sterke J de, Jadoul M, Guy R, Préat V. Assessment of the "Skin Reservoir" of Urea by Confocal Raman Microspectroscopy and Reverse Iontophoresis in vivo. Pharmaceutical Research DOI 10.1007/s11095-007-9314-42007, 2007
-
Caspers PJ, Lucassen GW, and Puppels GJ. Combined in vivo confocal Raman spectroscopy and confocal microscopy of human skin. Biophys. J. 85:572-580, 2003
-
Nijssen A, Bakker Schut TC, Heule F, Caspers PJ, Hayes DP, Neumann M, and Puppels GJ. Discriminating basal cell carcinoma from its surrounding tissue by Raman spectroscopy. J Invest Dermatol. 119:64-69, 2002
-
Caspers PJ, Lucassen GW, Carter EA, Bruining HA, and Puppels GJ. In vivo confocal Raman microspectroscopy of the skin: noninvasive determination of molecular concentration profiles. J Invest Dermatol. 116:434-442, 2001
-
Caspers PJ, Lucassen GW, Bruining HA, and Puppels GJ. Automated depth-scanning confocal Raman microspectrometer for rapid in vivo determination of water concentration profiles in human skin. J Raman Spectrosc. 31:813-818, 2000