Dr. Oliver Engelking
CellSystems
Biotechnologie Vertrieb GmbH
Hummelsberger Str. 11
53562 St. Katharinen
Germany
oliver.engelking@cellsystems.de
www.cellsystems.biz
Business
focus
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3D reconstructed human epidermal model EST-1000 for substance testing:
- Skin corrosivity (under ECVAM validation)
- Skin irritation (under ECVAM validation)
- Phototoxicity
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3D reconstructed human full thickness model AST-2000 for skin research:
- Efficacy testing
- Immunological assays etc.
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Human primary skin cells, selective cell culture media and reagents for skin research
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Contract research and contract testing on cells and on in vitro skin models
Important publications
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Hoffmann J, Heisler E, Karpinski S, Losse J, Thomas D, Siefken W, Ahr HJ, Vohr HW, Fuchs HW Epidermal-skin-test 1000 (EST-1000)--a new reconstructed epidermis for in vitro skin corrosivity testing. Toxicol In Vitro. 2005 ct;19(7):925-9. Epub 2005 Aug 2
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J. J. Hoffmann, P. Peters, P. Frost, H. W. Fuchs: Advanced Skin Test 2000 (AST-2000) Reconstructed Human Skin designed for dermatological and Pharmaceutical Research. European Journal of Cell Biology 82, Suppl. 53 (2003) S2-14
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E. Heisler, J.J. Hoffmann, P. Peters, H.-J. Ahr, H.-W. Vohr: Advanced Skin Test 2000 (AST-2000) as a Potent In Vitro Tool for the Characterization of Skin Reactions by Protein Fingerprinting. Toxicology Letters 144-1 (2003) S44
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E. Heisler, J. J. Hoffmann, P. Peters, H.-J. Ahr, H.-W. Vohr: Discrimination between local irritancy/cytotoxicity vs. immune reactions in vitro: 3D skin models as helpful tools in immunotoxicology. Immunobiology 206 (2002) 209