Dr. Marina Guerrin
UMR
5165
Faculty of Medicine
CNRS-University of Toulouse III
37 allees J. Guesde
31073, Toulouse
France
mweber@udear.cnrs.fr
Research
focus
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Transcriptome analysis of granular keratinocytes
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Cloning and characterisation of epidermis late
expressed genes
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Functional analysis of keratinocyte secreted proteins:
Corneodesmosin, Dermokine, A2ML-1
Important publications
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Toulza E, Galliano M-F, Jonca N, Gallinaro H, Méchin M-C, Ishida-Yamamoto A, Serre G, and Guerrin M. The human dermokine gene: description of novel isoforms with different tissue-specific expression and subcellular location. J. Invest. Dermatol., (in press), 2006
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Galliano MF, Toulza E, Gallinaro H, Jonca N, Ishida-Yamamoto A, Serre G, and Guerrin M. A novel protease inhibitor of the alpha 2 macroglobulin family expressed in the human epidermis. J. Biol. Chem. 2005 Nov 18; [Epub ahead of print]
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Gallinaro H, Jonca N, Langbein L, Vincent C, Simon M, Serre G, and Guerrin M. A 4.2 kb upstream region of the human corneodesmosin gene directs site-specific expression in hair follicles and hyperkeratotic epidermis but not in normal epidermis of transgenic mice. J. Invest. Dermatol., 122:730-738, 2004
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Guerrin M, Ishigami A, Méchin M-C, Nachat R, Valmary S, Sebbag M, Simon M, Senshu T, and Serre G. cDNA cloning, gene organization and expression analysis of human peptidylarginine deiminase type I. Biochem. J. 370:167-174, 2003
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Jonca N, Guerrin M, Hadjiolova K, Caubet C, Gallinaro H, Simon M, and Serre G. Corneodesmosin, a component of epidermal corneocyte desmosomes,displays homophilic adhesive properties. J. Biol. Chem. 277:5024-5029, 2002