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Prof. Sirkku Peltonen

Department of Dermatology
University of Turku and Turku Unversity Hospital
PL 52
20521 Turku
Finland
sirkku.peltonen@tyks.fi


Research focus

  • Intercellular junctions of epidermis, peripheral nerve and neural tumors

  • Neurofibromatosis




Important publications

  • Pummi K, Malminen M, Aho H, et al. Epidermal tight junctions: ZO-1 and occludin are expressed in mature, developing, and affected skin, and in vitro differentiating keratinocytes. J Invest Dermatol 2001;117:1050-8

  • Malminen M, Koivukangas V, Peltonen J, et al. Immunohistochemical distribution of the tight junction components ZO-1 and occludin in regenerating human epidermis. Br J Dermatol 2003;149:255-60

  • Pummi KA, Heape AM, Grénman RA, Peltonen JTK, Peltonen SA: Tight junction proteins, ZO-1, occludin, and claudins in developing and adult human perineurium. J Histochem Cytochem, 2004; 52:1037-4

  • Pummi K, Aho H, Laato M, Peltonen J, Peltonen S: Tight junction proteins and perineurial cells in neurofibromas. J Histochem Cytochem. 2006;54:53-61

  • Peltonen S, Riehokainen J, Pummi K, et al. Tight junction components occludin, ZO-1, and claudin-1, -4 and -5 in active and healing psoriasis. Br J Dermatol 2007;156:466-72

  • Leinonen PT, Hägg PM, Peltonen S, Jouhilahti EM, Melkko J, Korkiamäki T, Oikarinen A, Peltonen J. Reevaluation of the normal epidermal calcium gradient, and analysis of calcium levels and ATP receptors in Hailey-Hailey and Darier epidermis. J Invest Dermatol. 2009;129:1379-87

  • Alanne MH., Peltonen J, Pummi K, Grènman R and Peltonen S: Tight Junction Proteins in Human Schwann Cell Autotypic Junctions. J Histochem Cytochem 2009;57: 523-29

  • Raiko L, Leinonen P, Hägg PM, Peltonen J, Oikarinen A, Peltonen S. Tight junctions in Hailey-Hailey and Darier's diseases Dermatology Reports 2009; volume 1:e1

  • Mahoney MG, Sadowski S, Brennan D, Pikander P, Saukko P, Wahl J, Aho H, Heikinheimo Bruckner-Tuderman L, Fertala A, Peltonen J, Uitto J, Peltonen S: Compound heterozygous desmoplakin mutations result in a phenotype with a novel combination of myocardial, skin, hair, and enamel abnormalities. J Invest Dermatol. 130:968-78, 2010

  • Peltonen S, Raiko L, Peltonen J. Desmosomes in developing human epidermis. Dermatol Res Pract 2010:698761. Epub 2010 Jun 1

 

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