Stephan Dähnhardt-Pfeiffer
Microscopy
Services Dähnhardt GmbH
Mühlenberg 10
24220 Flintbek
Germany
spfeiffer@microscopy-services.com
www.microscopy-services.com
Business
focus
- Visualisation
of the skin barrier by electron microscopy
- Invasive
(Punch Biopsy) and noninvasive (LBV) sampling methods
- Invasive
(Punch Biopsy) and noninvasive (LBV) sampling methods
- Full service
provider in light and electron microscopy with focus on skin research
- Transmission electron microscopy (TEM)
- Scanning electron
microscopy (SEM)
- Light and
fluorescence microscopy (LM / IFLM)
- Immunolabelling
(LM and TEM)
- Virus diagnostic
(TEM)
- Negative
Staining and/or ultrathin sectioning
- Negative
Staining and/or ultrathin sectioning
Important publications
-
J-M. Jensen, S. Pfeiffer, M. Witt, M. Bräutigam, C. Neumann, M. Weichenthal, T. Schwarz, R. Fölster-Holst, E. Proksch (2009) Different effects of pimecrolimus and betamethasone on the skin barrier in patients with atopic dermatitis. J Allergy and Clinical Immunology 123,5,1124-1133
-
S. Pfeiffer, E. Tannich and C. Schmetz (2007) High-pressure freezing and freeze substitution provides new information on nucleus ultrastructure in amoebae (E.Histolytica).Microscopy and Microanalysis, 13, p 154-155
-
J.M. Jensen, S. Pfeiffer, M. Witt, R. Fölster-Holst, E. Proksch (2007)
Pimecrolinus but not betamethasone treatment normalizes the strukture of the skin barrier in atopic dermatitis. Experimental Dermatology, 16 (3), p 231
-
J.M. Jensen, S. Pfeiffer, T. Akaki, J.M. Schroeder, M. Kleine, C. Neumann, E. Proksch, J. Brasch (2007) Barrier Function, Epidermal Differentation, and Human ß-Defensin 2 Expression in Tinea Corpris. J Invest. Dermatol 127, 1720-1727
- F. Egberts,
M. Heinrich, J.-M. Jensen, S.Winoto-Morbach, S.Pfeiffer, M.Wickel,
M.Schunck, J.Steude, P.Saftig, E.Proksch, S.Schütze (2004) Cathepsin
D is involved in the regulation of transglutaminase and epidermal
differentiation. J Cell Science 117:2295-2307
- J. Schulz, H.Hohenberg,
F.Pflücker, E.Gärtner, T.Will, S.Pfeiffer, R.Wepf, V.Wendel,
H.Gers-Barlag, K.P. Wittern (2002) Distribution of sunscreens on skin.
Adv Drug Deliv Rev 54:157-163
- G. Vielhaber,
L. Brade, B. Lindner, S. Pfeiffer, R. Wepf, U. Hintze, K.P. Wittern,
H. Brade (2001) Mouse anti-ceramide antiserum: a specific tool for
the detection of endogenous ceramide. Glycobiology 11:451-457
- S. Pfeiffer,
G. Vielhaber, J.P. Vietzke, K.P. Wittern, U. Hintze, R. Wepf (2000)
High-pressure Freezing Provides New Information on Human Epidermis:
Simultaneous Protein Antigen and Lamellar Lipid Structure Preservation.
Study on Human Epidermis by Cryoimmobilization. J Invest Dermatol
114:1030-1038
- V. Schreiner,
G. S. Gooris, S. Pfeiffer, G. Lanzendörfer, H. Wenck, W. Diembeck,
E. Proksch, J. Bouwstra (2000) Barrier Characteristics of Different
Human Skin Types Investigated with X-Ray Diffraction, Lipid Analysis,
and Electron Microscopy Imaging. J Invest Dermatol 114:654-660