European Epidermal Barrier Research Network

Important publications

Baudoux, B., Castanares-Zapatero, D., Leclercq-Smekens, M, Berna, N.. & Poumay, Y. (2000) The tetraspanin CD9 associates with the integrin 6 4 in cultured human epidermal keratinocytes and is involved in cell motility. Eur. J. Cell Biol. 79, 41-51
Smits, P., Poumay, Y., Tylzanowski, P., Karperien, M., Wouters, J., Ponec, M., Huylabroeck, D. & Merregaert, J. (2000) Differentiation-dependent alternative splicing and expression of the Extracellular Matrix Protein 1 (Ecm1) gene in human keratinocytes. J. Invest. Dermatol. 114, 718-724
De Potter, I.Y., Poumay, Y., Squillace, K. & Pittelkow, M.R. (2001) Human EGF Receptor (HER) family and Heregulins members are differentially expressed in epidermal keratinocytes and modulate differentiation. Exp. Cell Res. 271, 315-328
Coquette, A., Berna, N., Vandenbosch, A., Rosdy, M., De Wever, B., & Poumay, Y. (2003) Analysis of the induction and release of interleukin-1 (IL-1 ) and interleukin-8 (IL-8) in in vitro reconstructed human epidermis in order to predict in vivo skin irritation and/or sensitisation. Toxicology In Vitro 17, 311-321
Jans, R., Sartor, M., Jadot, M. & Poumay, Y. (2004) Calcium entry into keratinocytes induces exocytosis of lysosomes. Arch. Dermatol. Res. 296, 30-41. DOI: 10.1007/s00403-004-0469-0
Jans, R., Atanasova, G., Jadot, M. & Poumay, Y. (2004) Cholesterol depletion upregulates involucrin expression in epidermal keratinocytes through activation of p38. J. Invest. Dermatol. 123, 564-573. DOI : 10.1111/j.0022-202x.2004.23221.x
Poumay, Y., Dupont, F., Marcoux, S., Leclercq-Smekens, M., Hérin, M. & Coquette, A. (2004) A simple reconstructed human epidermis : preparation of the culture model and utilization in in vitro studies. Arch. Dermatol. Res. 296, 203-211. DOI 10.1007/s00403-004-0507-y
Poumay, Y. & Coquette, A. (2007) Modelling the human epidermis in vitro: tools for basic and applied research. Arch. Dermatol. Res. 298, 361-369. DOI:10.1007/s00403-006-0709-6
Nikolova, E., Mitev, V., Minner, F., Deroanne, C.F., & Poumay, Y. (2008) The inhibition of the expression of the small Rho GTPase Rac1 induces differentiation with no effect on cell proliferation in growing human adult keratinocytes. J. Cell. Biochem., 103 (3), 857-864.DOI 10.1002/jcb.21455
Mathay, C., Giltaire, S, Minner, F., Bera, E., Hérin, M. & Poumay, Y. (2008) Heparin-binding EGF-like growth factor is induced by disruption of lipid rafts and oxidative stress in keratinocytes and participates in the epidermal response to cutaneous wounds. J. Invest. Dermatol., 128(3), 717-727. doi:10.1038/sj.jid.5701069
Lambert, S., Ameels, H., Gniadecki, R., Hérin, M. & Poumay, Y. (2008) Internalization of EGF receptor following lipid rafts disruption in keratinocytes is delayed and dependent on p38 MAPK activation. J. Cell. Physiol., 217, 834-845. DOI: 10.1002/jcp.21563
Minner, F. & Poumay, Y. (2009) Candidate house-keeping genes require evaluation before their selection for studies of human epidermal keratinocytes. J. Invest. Dermatol, 129, 770-773. doi:10.1038/jid.2008.247
Giltaire, S., Herphelin, F., Hérin, M., Stoppie, P. & Poumay, Y. (2009) The CYP26 inhibitor R115866 potentiates the effects of all-trans-retinoic acid on cultured human epidermal keratinocytes. Br. J. Dermatol., 160, 505-513. doi 10.1111/j.1365-2133.2008.08960.x
Mathay, C. & Poumay, Y. (2010) Lipid rafts and the oxidative stress hypothesis. J. Invest. Dermatol. 130, 1457-1459. doi:10.1038/jid.2009.425
Bertrand-Vallery, V., Belot, N., Dieu, M., Delaive, E., Ninanne, N., Demazy, C., Raes, M., Salmon, M., Poumay, Y., Debacq-Chainiaux, F. & Toussaint, O. (2010) Proteomic profiling of human keratinocytes undergoing UVB-induced alternative differentiation reveals TRIpartite Motif protein 29 as a survival factor. PLos ONE, 5 (5), e10462